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Is marijuana use an unspoken rule for posting on WATMM?


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Caffeine seems pretty out there if spiders are to be trusted. I guess alcohol would kill it?

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I consume Rick Simpson Oil, Distillate and bits of Shatter

Everyday

For once I can't remember

last time I was ill:)

I'll be 27 years in remission from cancer May 13, 2020

Cannabis is Magic:)

Cannabis compound could be weapon in fight against superbugs

Mice cured of MRSA, raising hopes of treating antibiotic-resistant bacteria

https://www.theguardian.com/society/2020/jan/19/cannabis-compound-could-be-weapon-in-fight-against-superbugs

Ian Sample

Sun 19 Jan 2020 15.07 GMT

A compound made by cannabis plants has been found to wipe out drug-resistant bacteria and break down persistent films of the microbes, raising hopes for a new weapon in the fight against superbugs.

Scientists screened five cannabis compounds for their antibiotic properties and found that one, cannabigerol or CBG, was particularly potent at killing methicillin-resistant Staphylococcus aureus or MRSA, one of the most common hospital superbugs.

Tests in the lab showed that CBG, which is not psychoactive, killed common MRSA microbes and “persister” cells that are especially resistant to antibiotics and which often drive repeat infections. The compound also cleared up hard-to-shift “biofilms” of MRSA that can form on the skin and on medical implants.

Having seen how effective the substance was against bacteria in the lab, the researchers decided to test CBG’s ability to treat infections in animals. In a new study, which has not yet been published, they found that CBG cured mice of MRSA infections as effectively as vancomycin, a drug widely considered the last line of defence against drug-resistant microbes. The study is under review at the ACS Infectious Diseases journal.

Eric Brown, a microbiologist who led the work at McMaster University in Hamilton, Ontario, said cannabinoids were “clearly great drug-like compounds”, but noted it was early days in assessing the compounds for use in the clinic. “There is much work to do to explore the potential of the cannabinoids as antibiotics from the safety standpoint,” he said.

Antibiotic resistance has become a major threat to public health. England’s former chief medical officer Dame Sally Davies has warned that the loss of effective antibiotics would lead to “apocalyptic scenarios”, with patients dying from routine infections and many operations becoming too risky to perform.

In the study, the researchers describe how the rapid global spread of drug resistance, caused by microbes developing mutations that protect them against antibiotics, has driven an urgent need to explore new sources of drugs. Among antibiotics in use today, the newest date back to discoveries made more than 30 years ago.

Bacteria fall into two classes depending on the makeup of their cells. MRSA bugs are known as gram positive bacteria, and have a single, thick cell membrane. Gram negative bugs differ in having inner and outer cell membranes and these infections can be harder to treat. In the World Health Organization’s priority list of drug-resistant bacteria, all three ranked as a “critical” priority are gram negative, namely Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacteriaceae.

Brown found that CBG and other cannabinoids did not work well against gram negative multi-drug resistant bugs. But the team went on to show that when CBG was used with small quantities of polymyxin B, an existing antibiotic that disrupts the outer membrane of gram negative bacteria, the cannabis compound wiped out the drug-resistant pathogens.

Cannabis plants are thought to make the compounds to fight off invading pathogens, but there are other ways to produce CBG. To study the compound, Brown’s team synthesised it in the lab using the chemicals olivetol and geraniol. “We are now pursuing the required paperwork to work with a wide variety of cannabinoids,” he said.

Mark Blaskovich, who studies antibiotic cannabis compounds at the University of Queensland, said cannabis seemed to be particularly rich in antibiotics, though other plants such as tea tree, garlic and the spices turmeric and curcurmin also contained antibacterials.

“These are likely made as a defence mechanism to protect the plant from bacterial and fungal infections, but to date have not been very useful for human infections as they really only work outside the body,” he said. “That’s what makes this new report potentially exciting – evidence that cannabigerol is able to treat a systemic infection in mice.”

https://www.theguardian.com/society/2020/jan/19/cannabis-compound-could-be-weapon-in-fight-against-superbugs

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4 hours ago, yekker said:
13 hours ago, Rubin Farr said:

But does it work on farts?

I'm pretty sure that's how you calibrate it 

it can calculate

down to the ppm

percentage of THC/CBD or any other cannabinoids

digested

and

released

into the air

of the

immediate

surrounding area

of the

brown dumpster

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On 1/20/2020 at 9:36 PM, DavieAddison said:

Anyone know any good shops in Rotterdam? I've been to a ton in Amsterdam but I'm going to Rotterdam for the first time this week

Trefpunt was alright. Weed was above average, a bit pricey like everywhere in Rotterdam. And they offer coffee for but a euro and free sandwiches, at least they did when I was there ?‍♀️

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Quote

Hey HempElf fans,

We are happy to announce our limited time pop up shop, Leefy, located at 67B Neal St. is up and running.

Come in during the first 3 days to receive 25% off all The Goods CBD products in store. 

If you happen to miss out on that deal, don't worry, we have sales running all month. For instance, buy 2 of The Goods concentrates and receive the 3rd 50% off. 

Even better, swing by and sign up to our mailing list and receive a CBD dab free of cost. 

If you are skeptical of our products, now's the time to see them in person! Check us out and see why everyone’s choosing HempElf for their CBD selections.

Covent Garden, check the shatters n waxes.......mmmmm mmmmmmmmmmmmm

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10 hours ago, Rubin Farr said:

"After sending THCP for lab testing, researchers found the compound bonded to human cannabinoid receptors 33 times more than THC did. "This means that these compounds have higher affinity for the receptors in the human body," Dr. Cinzia Citti, lead author of the study, told CNN.

As a result, THCP might generate stronger and faster reactions in the human body than other weed compounds. But researchers don't yet know whether THCP's effects on the human body could have medical uses or be psychoactive."

https://www.yahoo.com/news/scientists-discovered-marijuana-compound-thats-174300356.html

 

 

THCP

?

 

I Love this Reality:)

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On 2/6/2020 at 7:36 PM, Mesh Gear Fox said:

pffft that's got nothing on THPS

 

it blows my mind that some of yall live in places where you can just go to the store to get weed.

Tony Hawk Pro Skater? True. 

Yep, dispensaries are cool. The one I go to is actually in an old bank and looks awesome. But I can also get it delivered like pizza, it just takes longer than pizza. 

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