diatoms
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Posts posted by diatoms
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found on: https://old.reddit.com/r/Retconned/comments/x4f5ip/remember_spacetime_isnt_real/
Fascinating and mind blowing theories/mathematics presented by Donald Hoffman to help figure out what reality truly is.
Donald Hoffman: Reality is an Illusion - How Evolution Hid the Truth | Lex Fridman Podcast #293
Truth vs Reality: How we evolved to survive, not to see what’s really there | Donald Hoffman
Entangling Conscious Agents, Donald Hoffman
Do we see reality as it is? | Donald Hoffman
Professor Donald Hoffman — The Case Against Reality | The Tim Ferriss Show
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Do not go gentle into that good night
Dylan Thomas 1914-1953
Do not go gentle into that good night,
Old age should burn and rave at close of day;
Rage, rage against the dying light.
"Rage, rage against the dying light"
is what I remember
now it's
"Rage, rage against the dying of the light."
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oops, wrong birthday on this doc
august 18, 1971
not aug 17
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EAT SHIT AND
DIELIVE!NHS patients struggling with superbugs to be offered poo transplants
Revolutionary treatment for C diff infections that transfers gut bacteria from healthy faeces given the green light by Nice
Hundreds of patients struggling to ward off superbugs are to be treated with poo transplants on the NHS using gut bacteria taken from healthy donors’ faeces.
The National Institute for Health and Care Excellence (Nice), the health regulator, has given the green light for a faecal microbiota transplant (FMT) to be offered to people who have been treated for two or more Clostridium difficile (C diff) infections without success.
The revolutionary treatment aims to restore a healthy population of gut bacteria in sick patients by transferring a batch of different gut bacteria and other microorganisms from healthy donor poo into the gut of the recipient.
C diff is a type of bacteria that can cause diarrhoea, and often affects people who have been taking antibiotics. People are more likely to get a C diff infection if they are over 65, have been staying in hospital or a care home for a long time, or if they have a weakened immune system – for example, from having a long-term condition such as diabetes or kidney failure, or treatments including chemotherapy.
It can usually be treated with a different type of antibiotic but is referred to as a superbug due to its resistance to treatment in some instances.
Nice said clinical trials showed that FMT treatments are significantly better than antibiotics alone at resolving a stubborn C diff infection.
The health regulator said it had been presented with evidence that the treatment could save the NHS thousands of pounds. It may also mean patients could take fewer antibiotics and experience a better quality of life after treatment, it added.
The new bacteria can be delivered through a tube inserted directly into the stomach through the nose, or alternatively be deposited directly into the colon through a tube or swallowed via a pill.
Mark Chapman, interim director of medical technology at Nice, said: “There is currently a need for an effective treatment of C diff in people who have had two or more rounds of antibiotics.
“Our committee’s recommendation of this innovative treatment will provide another tool for health professionals to use in the fight against this infection, while at the same time balancing the need to offer the best care with value for money.
“Use of this treatment will also help reduce the reliance on antibiotics and in turn reduce the chances of antimicrobial resistance, which supports Nice’s guidance on good antimicrobial stewardship.”
Nice said it made its decision after reviewing evidence from five trials of 274 adults.
The data showed that more C diff infections were resolved with FMT than antibiotic treatment in four of the trials and there was no difference in the other. FMT can lead to different levels of clinical cure depending on how the treatment is given but it could resolve up to 94% of infections, Nice said.
Modelling shows that poo transplants are cheaper than treatment with almost all antibiotics. They save the NHS about £769 if given using a colonoscopy, and as much as £8,297 if administered using an oral capsule. It costs £1,287 per patient more if given as an enema. But FMT via enema would only be an option for the minority who cannot have FMT by another route, Nice said.
Nice estimates that 450 to 500 people in England could be treated using FMT for multiple recurrences of C diff infections each year.
It said that a strict donor screening programme should be in place and that treatments should be manufactured in accordance with human medicine regulations.
baby hippos, elephants, koalas and pandas already eat their mother's feces for healthy bacteria
bon appétit
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On 8/29/2022 at 8:51 PM, Joyrex said:
Theme is now fixed
tomorrow's harvest theme doesn't have the same yellow/brown background as before
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lush rave
aphex twin - tha
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found on: https://old.reddit.com/r/Retconned/comments/wzdbxs/barbie_girl_by_aqua_reference_everything/
Everything Everywhere All At Once: Deleted Scene “Alternate (Barbie Girl) Ending”
"I'm a Barbie Girl, in a Barbie World"
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Staying Healthy
https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
The endocannabinoid system: Essential and mysterious
August 11, 2021- By Peter Grinspoon, MD, Contributor
Many of us have heard of some of the transmitter systems within our bodies, such as the sympathetic nervous system, which gives us our fight-or-flight response. Fewer have heard of the more recently discovered endocannabinoid system (ECS), which is amazing when you consider that the ECS is critical for almost every aspect of our moment-to-moment functioning. The ECS regulates and controls many of our most critical bodily functions such as learning and memory, emotional processing, sleep, temperature control, pain control, inflammatory and immune responses, and eating. The ECS is currently at the center of renewed international research and drug development.
What is the ECS?
The ECS comprises a vast network of chemical signals and cellular receptors that are densely packed throughout our brains and bodies. The "cannabinoid" receptors in the brain — the CB1 receptors — outnumber many of the other receptor types on the brain. They act like traffic cops to control the levels and activity of most of the other neurotransmitters. This is how they regulate things: by immediate feedback, turning up or down the activity of whichever system needs to be adjusted, whether that is hunger, temperature, or alertness.
To stimulate these receptors, our bodies produce molecules called endocannabinoids, which have a structural similarity to molecules in the cannabis plant. The first endocannabinoid that was discovered was named anandamide after the Sanskrit word ananda for bliss. All of us have tiny cannabis-like molecules floating around in our brains. The cannabis plant, which humans have been using for about 5,000 years, essentially works its effect by hijacking this ancient cellular machinery.
A second type of cannabinoid receptor, the CB2 receptor, exists mostly in our immune tissues and is critical to helping control our immune functioning, and it plays a role in modulating intestinal inflammation, contraction, and pain in inflammatory bowel conditions. CB2 receptors are particularly exciting targets of drug development because they don’t cause the high associated with cannabis that stimulating the CB1 receptors does (which is often an unwanted side effect).
The ECS's role in learning and memory
We know that the ECS plays a critical role in learning and memory due to several lines of research. The most obvious observation is that one of the main side effects of high dosages of recreational cannabis use is the temporary disruption of short-term memory. Memory returns to normal with abstinence. There have also been some sophisticated studies of how humans acutely respond to the administration of THC (the active ingredient in cannabis) and the ways in which this alters both their ability to memorize things in the short term and the patterns observed on their functional brain imaging.
According to the popular writer Michael Pollan in his bestselling book The Botany of Desire, cannabis is one of the plants that humans have cultivated, or co-evolved with, for thousands of years. This is in part, Pollan writes, because the act of forgetting plays a valuable role in the ability of our brains to function without being overloaded with data from our senses that we are continually bombarded with. Pollan hypothesizes that if we didn’t forget, we wouldn’t function, and cannabis helps us do this. The role that the ECS plays in forgetting also opens up opportunities for the treatment of PTSD, a condition in which there are unpleasant, intrusive memories that people can’t help but remember, and that cause a whole syndrome of troublesome and dangerous symptoms related to the pathological remembering.
The ECS's role in hunger and fine-tuning weight-loss medications
The cautionary tale of the drug rimonabant, a drug that blocks the CB1 receptor, is an interesting example of the central role the ECS plays in so many crucial functions. It was developed as an anti-obesity drug. The thinking was that the ECS controls hunger. We know this because, among other lines of evidence, cannabis gives you "the munchies," so if you block the CB1 receptor it should cause weight loss. Rimonabant did cause weight loss, quite successfully. But, because the ECS also regulates mood, it had to be withdrawn from the market on an emergency basis because people who were taking it were becoming suicidal. However, we can imagine a case, as we better understand the complexities of the ECS, where we may be able to create a weight-loss medication that acts on those cannabinoid receptors that affect weight loss, but that doesn’t act on those receptors that control mood.
Exploration of the ECS may lead to new drug discoveries
Study of the ECS was initially focused on attempts to understand (and demonize) an illegal drug, but new research has since flourished into a far more broad-based exploration into what is an astoundingly intricate and far-reaching system by which our bodies learn, feel, motivate, and keep themselves in balance. We are truly at the dawn of an age of discovery of the ECS and the development of new medicines that may help alleviate some of the cruelest diseases that people (and animals) suffer from. I am incredibly excited to see what discoveries await us as we continue to untangle the mysteries of the ECS.
https://www.health.harvard.edu/blog/the-endocannabinoid-system-essential-and-mysterious-202108112569
Peter Grinspoon, MD
Contributor
Dr. Peter Grinspoon is a primary care physician, educator, and cannabis specialist at Massachusetts General Hospital; an instructor at Harvard Medical School; and a certified health and wellness coach. He is the author of the forthcoming book Seeing Through the Smoke: Cannabis: Finding Truth Among Tangled Beliefs, as well as the groundbreaking memoir Free Refills: A Doctor Confronts His Addiction. He is a board member of the advocacy group Doctors for Cannabis Regulation. He is also a TedX speaker and commonly lectures on the topics of cannabis, psychedelics, addiction, opioids, and physician health.
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happy birthday rdj
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i'm also having trouble with the tomorrow's harvest theme not showing images/attachments
and for me it also shows this drop-down on every page
- Everywhere
- Topics
- More options...
Find results that contain...- Any of my search term words
- All of my search term words
Find results in...- Content titles and body
- Content titles only
On 8/13/2022 at 1:54 AM, Frank Poole said:Edit: Seems to just with the tomorrow's harvest theme
thanks for this:) it is only affecting this theme
so now i'm on watmm classic (default)
but tomorrow's harvest has a warmth no other theme has
some would agree about the album
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On 8/5/2022 at 6:06 PM, ReVoodle said:
Some guy on reddit posted this and then deleted his post. Wouldn't think too much about it if he hadn't deleted. Maybe he was just not wanting the heat from wild speculation to come down on him. Or perhaps....
i see the color of old chartreuse
On 11/11/2020 at 8:24 PM, diatoms said:RENO 911! : Law of Design : Clip : Season 5 Episode 14
Season 5 E 14 • 06/26/2008
A man wearing chartreuse glasses has a complaint about his neighbor's paint choices.
http://www.cc.com/video-clips/ix0f7l/reno-911--law-of-design
After responding to a 911 call, Williams and Wiegel are faced with a suspected law of design violation.Man in Chartreuse glasses: "I want to report a violation of the law, OK?The Law of Design! Have you seen the exterior paint colorthey're painting their trailer? [Laughs] Come On.I mean their trailer is, uh, Dutch colonial,and they're painting it Chartreuse?I mean, even I'm not that daring.Officer Williams: "I'm gonna help you out right now. If you take off your Chartreuse glasses,I think the color of that house might change, and we can go onand fight some real crime. Go on, look over there now.Man in Chartreuse glasses: "You know, it's not that bad."Officer Wiegel: "It's a great color."
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Inside The Unrecorded Lobby Meeting Between The Anti-Cannabis Group And The Drugs Minister
July 19, 2022 - BREAKING NEWS, LOCAL NEWS
WITH news that the Cannabis Risk Alliance (CRA) lobbied the junior minister responsible for the country’s drug strategy Frank Feighan without any notes or minutes recorded due to a loophole in the Lobbying Register, WWN has obtained secret transcripts of the meeting between Dr Ray Walley, Professor Mary Cannon, Dr Matthew Sadlier, Dr Bobby Smyth and Dr Hugh Gallagher on 26 January, 2021.
CRA: “Whasssssup, Frankie baby?”
FF: “Lads. what’s the fucking craic, these lockdowns eh? Enough to drive you to drink”
CRA: “Or weed… bahahahaha”
FF: “Just to confirm, no one’s recording this zoom meeting, right? You don’t need to record any meeting with me if none of you are working full-time at the Cannabis Risk Alliance”
CRA: “God no, handy loophole though”
FF: “Yeah, makes ya think who else is abusing it hahaha”
ALL PARTICIPANTS LAUGH
CRA: “Jesus, yeah, if this got out that we were all talking secretly to you, then us calling out the alcohol lobbyists actually registering the lobbying with politicians would look pretty hypocritical of us”
FF: “Don’t worry, that will never happen. Okay, so what have we this time round?”
CRA: “Well, we had a great idea to try stop cannabis being legalised and highlight the risks in the form of one of those RSA adverts. You know the ones were people get maimed and dead and stuff?”
FF: “Yeah, I know the ones… ‘can I tell you about my life… errrrcccchh’ [Minister Feighan sings song from old RSA ad while mimic driving before hilariously mimicking crash scene]”
CRA: “Hahaha spot on, exactly, yeah, only this time it’s not drink, it’s cannabis, and even more traumatic where the users brain explodes after smoking a joint, people strung out on the street begging, stealing handbags, that kind of thing”
FF: “Right! Sounds a bit extreme though?”
CRA: “Yeah, well cannabis is highly addictive and dangerous, so… “
FF: “Yeah, but, isn’t everything harmful if you do too much of it? Sure, you can be addicted to chocolate… “
EVERY MEMBER OF THE ALLIANCE CHASTISES THE MINISTER FOR HIS CASUAL REMARK FOR SEVERAL MINUTES BEFORE CONTINUING
FF: “Okay, okay, I get how passionate you guys are and want to be seen among your peers as being at the forefront of keeping it illegal – that’s great – but this cannabis thing is a real pain in my balls; the government don’t want to seem anti or pro weed and prohibition is only funding crime gangs here and forcing dangerously high cannabis into the black market. If we regulate its strength so it’s not so harmful to people and use the VAT proceeds from its sale to educate young people into the possible dangers, then surely thats the best road to take going forward?
EVERY MEMBER OF THE ALLIANCE CHASTISES THE MINISTER FOR HIS CASUAL REMARK FOR SEVERAL MINUTES BEFORE CONTINUING
FF: “All I’m saying is that cannabis seems to be helping a lot of people with a lot of different ailments, from epilepsy to anxiety and depression, taking them off harmful prescription drugs while also being an exit drug for some hard drug addicts as opposed to a gateway drug as stigmatised by a lot of opposers.
EVERY MEMBER OF THE ALLIANCE CHASTISES THE MINISTER FOR HIS CASUAL REMARK FOR SEVERAL MINUTES BEFORE CONTINUING
FF: “Aw fuck it, lads, look, I tell you what; we’ll keep fobbing this off until the next government comes in and has to deal with it, okay? Chat to you all again, I’m sure… of course, without registering it with the Lobbying Register bahahahaha”.
EVERYONE LAUGHS
CRA: “Thanks, Frank. Just keep the status quo and let us medical professionals decide everything – it’s never gone wrong in the past”.
CALL ENDS BEFORE DRUGS MINISTER ROLLS UP A BIG FAT ONE
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On 3/23/2017 at 4:27 AM, diatoms said:
Jiffy peanut butter
found on https://old.reddit.com/r/Retconned/
American Dad - Season 2, Episode 13
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"Aphex Twin's butt image ended up on album covers and music videos directed by Chris Cunningham"
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Tuss
in Aphex Twin
10 minutes ago, tbf said:what does that got to do with the afex twins?
some people think karen & brian are twins but they're really just sis & bro
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2 hours ago, prdctvsm said:
Robert Knupp is a Professor inthe Department of Music. Professor Knupp joined MC’s faculty in 2000 and currently teaches Music Theory III and IV, Applied Organ, Applied Piano, and Popular Music and Society. His areas of expertise include the pipe organ and music theory.Professor Knupp has playedorgan recitals in 29 states, been heard on the nationally broadcast "Pipedreams" program, and has played in places such as the Washington National Cathedral and St Thomas Church in Leipzig, Germany.Dr Knupp is also the organist at Galloway UnitedMethodist in Jackson.i made bold the letters that spell out in his bio
steinVord
sorry prof knupp caught ya
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the real gem to look for is a burned caustic window cd
& watmm
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6 hours ago, prdctvsm said:
Prof. Robert B. Knupp, Finland
findland?
everyone knows he's a professor in the department of music at mississippi college
no "B." either
maybe
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38 minutes ago, MIXL2 said:
i really liked this video and the others, thanks:)
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hologram of sean slowly shaking his head
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On 7/5/2022 at 11:11 AM, Psychotronic said:
ANY ANSWER RAISES MORE QUESTIONS...
have to agree with ya ai
but my ? is why start with a lambda
wait... don't answer that
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3 hours ago, Rubin Farr said:
Runnin up that hill
yeah tried runnin today and realized there's lots o bush in the way
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got one-punch man vol. 1, 3-6 & 8 but missing 2 & 7 from the public library for tomorrow
motivation to get in shape 100 sit-ups, 100 push-ups and 100 squats
i live on the side of a hill so i'll run up and down for a while to round it out
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everytime i get in the car this summer i seem to always put this song on first
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Queen Elizabeth II (1926-2022)
in General Banter
Posted
thought the same:)